Self-measurement of ‘Blood Pressure’ (BP) leads to less use of anti-hypertensive drugs but worse blood pressure control based on ambulatory measurements, a randomized controlled trial research study has recently concluded.
These findings of the research study were published in the current issue of the journal “Hypertension”. This research included controlled trials and come from the ‘Home versus Office Measurement’. This study also included the ‘Reduction of Unnecessary Treatment Study (HOMERUS)’, a multicenter prospective double-blind trial.
The research study involved 430 adult participants in all and every one of them were with systolic blood pressure of more than 139mmHg or diastolic blood pressure of more than 89 mmHg. These participants were randomly assigned to receive anti-hypertensive therapy based on either office or self BP measurement. Researchers fixed the target blood pressure for both groups was 120-139 systolic and 80-89 mmHg diastolic BP.
Willem Verberk and co-authors at the “University Hospital Maastritch”, The Netherland reported in their research study report that the Medication use, that turns ultimately in to the drug cost, was significantly lower in the self-measurement group.
The study findings indicate that the mean number of “drug steps” i.e. changes in medication, was 1.47 in the self blood pressure measurement group versus 2.48 in the office BP group .Study results also showed that 54.0% of self BP measurement patients reached a stable treatment level in comparison to those who belonged to the office group with 48.0% .
Researchers found that despite these medication differences between these two comparable groups, both the groups achieved similar reductions in systolic and diastolic blood pressure, left ventricular mass, and median urinary micro albumin level.
Researchers observed that 24-hour ambulatory BP values (ABP) were higher in the self- measurement group. At the end of the study period, median ABP was 125.9/77.2 mmHg in the self-measurement group compared to 123.8/76.1 mmHg in the office group. Researchers said that it is a statistically significant difference overall.
“Although this could mean that antihypertensive treatment based on self-measurement leads to worse BP control, we must realize that the reproducibility of ABP measurement is limited”, said the lead researcher Willem Verberk in the published study report.
Willem Verberk and co-authors conclusively remarked about the research study, “These results cannot be ignored, because even small differences can have serious consequences with respect to cardiovascular complications in the population at large”.
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These findings of the research study were published in the current issue of the journal “Hypertension”. This research included controlled trials and come from the ‘Home versus Office Measurement’. This study also included the ‘Reduction of Unnecessary Treatment Study (HOMERUS)’, a multicenter prospective double-blind trial.
The research study involved 430 adult participants in all and every one of them were with systolic blood pressure of more than 139mmHg or diastolic blood pressure of more than 89 mmHg. These participants were randomly assigned to receive anti-hypertensive therapy based on either office or self BP measurement. Researchers fixed the target blood pressure for both groups was 120-139 systolic and 80-89 mmHg diastolic BP.
Willem Verberk and co-authors at the “University Hospital Maastritch”, The Netherland reported in their research study report that the Medication use, that turns ultimately in to the drug cost, was significantly lower in the self-measurement group.
The study findings indicate that the mean number of “drug steps” i.e. changes in medication, was 1.47 in the self blood pressure measurement group versus 2.48 in the office BP group .Study results also showed that 54.0% of self BP measurement patients reached a stable treatment level in comparison to those who belonged to the office group with 48.0% .
Researchers found that despite these medication differences between these two comparable groups, both the groups achieved similar reductions in systolic and diastolic blood pressure, left ventricular mass, and median urinary micro albumin level.
Researchers observed that 24-hour ambulatory BP values (ABP) were higher in the self- measurement group. At the end of the study period, median ABP was 125.9/77.2 mmHg in the self-measurement group compared to 123.8/76.1 mmHg in the office group. Researchers said that it is a statistically significant difference overall.
“Although this could mean that antihypertensive treatment based on self-measurement leads to worse BP control, we must realize that the reproducibility of ABP measurement is limited”, said the lead researcher Willem Verberk in the published study report.
Willem Verberk and co-authors conclusively remarked about the research study, “These results cannot be ignored, because even small differences can have serious consequences with respect to cardiovascular complications in the population at large”.
Discuss Add this link to... Bury
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