In the nearly 100 years that have elapsed since DDT was first synthesised, this substance has had an influence on human ecology perhaps unmatched by any other synthetic substance. It has had signal success in the control of insect pests of agriculture and, through its effectiveness in the conquest of malaria, typhus, and other insect-borne diseases, it has played a decisive role in the population explosion. It has also become the classic example of an environmental micropollutant. Significant discoveries about the chemistry of DDT and its analogues are still being made. These have considerable theoretical interest in studies of the enigmatic mode of action of DDT and are of applied interest in control of resistant insects and in environmental quality control.
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