The Indianapolis Colts will try and avoid a letdown this week as they play the San Diego Chargers on Sunday night. The Colts are coming off perhaps the biggest regular season game in history as they lost last week 24-20 to the New England Patriots. The Colts had a 20-10 lead in the fourth quarter before letting it slip away. "That hurts the most," cornerback Kelvin Hayden said. "The main thing we have to focus on is the fourth quarter, and that's something we've got to learn from." SBG Global reports that early NFL betting has the public taking Colts on the Road.

The Colts have to really guard against a letdown on Sunday since they had a similar situation happen last year after starting 9-0. "We had the same situation last year when we went to Dallas and had the lead and couldn't hold it and then we got into a stretch where we didn't play very good football," Colts coach Tony Dungy said. "This is the same thing as last year. So we've got to bounce back and do it a little better than last year. I think we know what's at stake and we can't afford a letdown after this loss."
SBG Global Current Line: Colts -3.5 (-115) , Total 48

The Chargers will try and bounce back from a 35-17 loss at Minnesota where Adrian Peterson ran all over them for an NFL single-game record 296 yards. The Chargers were thought to be a contender in the AFC but have not played well this season. "We're not an elite team at all," Tomlinson said. "We're a team that's in the middle of the pack and we're struggling trying to win games. We've got to find a way to get back to playing successful football and playing the way we're able to play when we're good. We've got to start beating teams that are good and teams that are elite in this league."

Here are the NFL betting stats for Sunday’s game. The Colts are 4-0 ATS in their last 4 games as a favorite. The Colts are 6-2 ATS in their last 8 vs. the AFC. The Colts are 9-3 ATS in their last 12 games in November. The Colts are 2-5 ATS in the last 7 meetings between the two teams but the road team is 5-2 ATS in the last 7 meetings.

The Chargers are 13-3-2 ATS in their last 18 games as an underdog. The Chargers are 0-4 ATS vs. a team with a winning record.

The Under is 5-1 in the Colts last 6 games on grass. The Under is 5-1 in the Colts last 6 road games. The Over is 7-1 in the Chargers last 8 games as a home underdog. The Over is 12-3 in the Chargers last 15 games in November. The Over is 5-2 in the Chargers last 7 games overall. The Over is 5-2 in the last 7 meetings between the two teams.
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